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KMID : 0387420170280040349
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Korean Society of Oriental Neuropsychiatry
2017 Volume.28 No. 4 p.349 ~ p.358
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Analysis of Clinical Research Trends on Traditional Chinese Medicine Treatment for Depression Syndrome Similar to Hwabyung: Focusing on CNKI
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Choi Eun-Ji
Suh Hyo-Weon
Kim Jong-Woo
Jung Seon-Yong
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Abstract
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Objectives: To analyze whether a concept similar to Korean ‘Hwabyung’ exists in China. We inves-tigated the status of clinical studies conducted in China for relevant diseases and trends of the tradi-tional Chinese medicinal (TCM) treatment adopted in clinical studies.
Methods: To explore the concept of a condition similar to Korean Hwabyung in China, we searched for the existence of concept and pattern that were parallel or similar to those of Hwabyung in TCM text-books and diagnostic guidelines. We searched and analyzed clinical studies of TCM treatment for de-pression syndrome similar to Hwabyung from CNKI using terms 'depression' and 'qi stagnation trans-forming into fire'. Using extracted data, characteristics of clinical research, herbal medicine, and acu-puncture treatment used in the clinical research and their effects were systematically reviewed.
Results: Symptoms of 'qi stagnation transforming into fire' were most similar to those of Hwabyung. Nine articles were selected from a total 258 articles. Most of them used DSM-IV or CCMD-3 for depres-sion diagnosis. They applied 'diagnostic and efficacy guidelines for TCM diseases and syndromes' for pattern diagnosis of 'qi stagnation transforming into fire'. Danzhixiaoyao-san and Jiaweixiaoyao-san were found to be effective when they were used alone or in combination with antidepressants. Acupuncture treatment also showed remarkable effect on LR3, HT7, LI4, PC6, GV20 when it was used alone or in combination with antidepressants. However, careful interpretation is required because a small number of studies are included.
Conclusions: 'Qi stagnation transforming into fire' seemed to have symptoms similar to Hwabyung. However, further research is needed to determine its diseases and pattern types compared to Hwabyung. According to included studies of 'depression with Qi stagnation transforming into fire', herbal medicine and acupuncture treatment tended to be effective in relieving depressive symptoms. However, more discussion is required for future application of herbal medicine and acupuncture for treating Hwabyung.
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KEYWORD
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Hwabyung, Depression, Herbal Medicine, TCM, Clinical Studies
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